The Effects of Fatigue on Exercise-Induced Hypoalgesia

The purpose of this study is to understand how different intensities (or how hard an exercise is) of a leg exercise with weights potentially change your threshold for pain. We also want to understand how different psychological factors, such as fear, and other factors, such as sleep or physical activity, can be used to predict the amount of pain reduction after resistance exercise.

During this study, you will attend three sessions that are about 30 minutes-1 hour each in which you will complete forms and undergo assessment of your pain sensitivity through exposure to heat, cold, and pressure stimuli. You will be performing a knee extension exercise of your dominant leg for 3 sets at different fatiguing levels.

Inclusion Qualifications:

  • Pain-free
  • 18-60 years old
  • Participant can appropriately perform the knee extension exercise (assessed during screening)

Exclusion Qualifications:

You may not participate in this research opportunity if any of the following applies to you:
  • Regular use of prescription pain medications
  • Current or history of chronic pain condition
  • Currently taking blood-thinning medication
  • Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions
  • Any contraindication to the application of ice, such as: uncontrolled hypertension (blood pressure over 140/90 mmHg), cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise
  • Known presence of cardiovascular, pulmonary, or metabolic disease
  • Current use of tobacco products
  • Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
  • Surgery, injury, or fracture to the lower back or lower extremity within the past 6 months

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UCF IRB#: 00004630 ID
PI: Abigail Wilson
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Recruitment End Date:
April 5, 2023
Education Complex and Gym
12494 University Boulevard
Room 174A
Orlando, FL 32816
Time Commitment:
Number of visits: 3
Expected time per visit: 30 minutes
Point of Contact:
Riley Hogge
Faculty Advisors:
Abigail Anderson
Associated Units:
Athletic Training
Physical Therapy
Exercise Physiology & Rehabilitation Science
Short URL:

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