Rehydration and Dehydration Recovery

This research study is looking at a commercially available hydration drink designed for preventing or treating dehydration. The research will help determine there are any benefits for adults consuming an oral rehydration solution after passive dehydration.

Study participation will last about 2-3 weeks and will include a screening visit and 2 study visits.

The screening visit will determine if you meet all the criteria and introduce you to the study procedures. You will then return for 2 study visits, separated by at least 3 days, where you will drink a commercially available hydration drink that contains electrolytes, glucose and zinc. You will have urine, saliva and blood samples taken at each visit, sit in an infrared sauna, drink study product, complete questionnaires on how you feel and do some additional strength and reaction time procedures.

Inclusion Qualifications:

  • You are 18 to 40 years of age.
  • You have a body mass index (BMI) ≥ 18 and ≤ 30 kg/m2.
  • You report having a moderate to heavy sweat rate when physically exerted or in extreme heat.
  • You are male or non-pregnant, non-lactating female, at least 6 weeks postpartum prior to screening visit. A urine pregnancy test is required for all females unless you are not of childbearing potential. If you are of childbearing potential, you must be practicing one of the following methods of birth control (and will continue through the duration of the study): Condoms, sponge diaphragm, intradermal patch or intrauterine device; oral or parenteral contraceptives for 3 months prior to screening visit; vasectomized partner; or total abstinence from sexual intercourse.
  • You have normal blood pressure, ≤ 120/80 mm Hg, without the use of blood pressure medications.
  • You report no predisposing cardiovascular (heart) conditions.
  • If female, you have a regular menstrual cycle, >21 days and <35 days in length.
  • You are willing to consume grape-flavored beverages during the study.
  • If you are on chronic medication such as lipid-lowering, thyroid medication or hormone therapy, the dosage must be constant for at least 2 months prior to screening and baseline visit. You must be able to maintain medication type and dose throughout duration of study.
  • You are weight-stable for the two months prior to screening visit (has maintained current body weight within 4 kg or about 9lbs).
  • You must voluntarily sign and date this informed consent form, approved by the UCF IRB, and provided applicable privacy regulation authorization prior to any participation in the study.
  • You have no known intolerance or allergy to ingredients in study products.
  • You are willing to refrain from using saunas or hot tubs for the duration of the study, outside of trial procedures.
  • You are able and willing to follow study procedures and complete any forms or assessments needed during the study.

Exclusion Qualifications:

You may not participate in this research opportunity if any of the following applies to you:
  • You are a current, and including the past 8 weeks, participant in a weight-conscious sport such as but not limited to wrestling, powerlifting, boxing, rowing, gymnastics or any martial arts, with participation defined as ≥ 3x weekly training.
  • You are currently, and for the past 4 weeks or longer: running >40 miles per week on average, cycling >80 miles per week on average or swimming >20,000 yards per week on average.
  • You are participating in another study that has not been approved as a concomitant (jointly enrolled in) study by Abbott (the study sponsor).
  • You have used a sauna in the past 4 weeks.
  • You use any form of tobacco or nicotine, or other controlled substance not prescribed by a physician, or medical marijuana.
  • You have previous history with heat illness or injury that resulted in a visit to a medical center in the past 12 months.
  • You have an eating disorder, severe dementia or delirium, history of significant neurological or psychiatric disorder, alcoholism, substance abuse or other conditions that may interfere with study product consumption or compliance with study protocol procedures.
  • You are currently taking or have taken antibiotics within 6 weeks of enrollment.
  • You are currently taking or has taken a diuretic within 1 week of enrollment.
  • You have been diagnosed with the following according to self-report or according to the investigator’s judgment:
    Recent or current acute or chronic infections including but not restricted to respiratory infections, diarrhea, Hepatitis B or C, HIV infection or tuberculosis;
    Severe gastrointestinal disorders such as celiac disease, short bowel syndrome, pancreatic insufficiency, or cystic fibrosis;
    Metabolic [including diabetes], renal, hepatic, or respiratory disease;
    Active malignancy;
    Polycystic ovary disease;
    Any other clinically significant medical condition, which in the investigator’s opinion, makes him or her unsuitable for inclusion in the study

Participate in this Research

Submitting this form will put you in contact with the main point of contact for this project. They will provide more information and determine if you meet all of the qualifications needed.

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* Please note that completion of this form does not automatically enroll you or guarantee you a spot in this research opportunity. The information provided in this form will never be shared with 3rd parties. You can also unsubscribe from future notifications at any time.
UCF IRB#: STUDY00006001
PI: Dr. David Fukuda
Recruitment End Date:
June 1, 2024
Education Complex
12494 University Blvd
Room 174
Orlando, FL 32816
Time Commitment:
Number of visits: 2
Expected time per visit: 8 hours
Type: $800 in Gift Cards
Point of Contact:
Modesto Lebron
Faculty Advisors:
David Fukuda
Associated Units:
Related Tags:
Short URL:

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