Melatonin & Recovery
The purpose of this study is to examine the effect of melatonin supplementation on how your white blood cells respond to resistance exercise and influence recovery from muscle damage. Additionally, we will examine physical performance, sleep quality and duration, as well as ratings of stress and soreness from pre-exercise to several time points post-exercise to determine the impact of the exercise and supplement on performance these measures.
How long will the research last and what will I need to do?
We expect that you will be in this research study for approximately 10.25 hours over 2 weeks, or as long as it takes to complete 5 visits. You will be asked to complete one consent visit, one familiarization visit, and three testing sessions. The sessions will involve surveys, exercises, and blood draws.
Inclusion Qualifications:
- Male or female between the ages of 18-40 years old.
- Healthy and ready for physical activity as determined by questionnaires you complete about your health status.
- Currently resistance training and have trained for a minimum of 6 months. To be included, you must have completed 3 resistance training sessions (defined as muscle strengthening activities such as free weights, weight machines, or calisthenics, etc.) per week with at least one lower body session. This will be determined by a Training History Questionnaire (THQ).
- Premenopausal, with a regular menstrual period as determined by the menstrual status questionnaire (female participants only).
- Currently not pregnant and do not intend to become pregnant (female participants
only). - Currently not taking dietary supplements that may affect study outcomes (e.g., creatine, beta-alanine) and willing refrain from taking such supplements while enrolled in the study. If you are currently using such supplements, you will be permitted to enroll in the study after not taking such supplements for a period of four weeks.
- Willing to adhere to all pre-testing visit instructions including abstaining from exercise for the duration of the study and abstaining from alcohol for 24 hours prior to each study visit.
- Currently consuming ≤ 300mg caffeine (≤ three 8oz cups of coffee) per day on average and willing to keep caffeine intake consistent throughout the duration of the study. Also willing to avoid caffeine intake for 12 hours prior to visits 3, 4 and 5 and not consume caffeine the morning of these visits.
- Free from previous or current lower body injuries that may limit your ability to complete either exercise or physical assessments.
- Highly likely to be successful at providing the required blood samples. This will be determined during visit 1 by a certified phlebotomist.
- Not regularly taking any type of prescription or over-the-counter medication which might affect the assessments, or having any chronic illnesses, which require medical care. This will be determined in your medical history questionnaire.
Exclusion Qualifications:
You may not participate in this research opportunity if any of the following applies to you:- Individual does not agree to participate in this study.
- Individual does not meet inclusion criteria to participate in the study protocols as determined via the PAR-Q+, medical history questionnaire, training history questionnaire, and/or the caffeine consumption questionnaire.
- Currently taking melatonin (MEL)
- Regularly taking any type of prescription or over-the-counter medication which might affect the assessments, or having any chronic illnesses, which require medical care.
- Not currently meeting requirements for resistance trained status.
- Current known pregnancy or intent to become pregnant during the study period.
- Not regularly having periods or amenorrheic, as determined by MSQ.
- Currently taking any performance-enhancing drug (determined from health and activity questionnaire).
- Currently taking a nutritional supplement viewed by the research team to confound the outcomes of the study and not willing to abstain from taking the supplement during the course of the study or not willing to undergo a 4-week wash-out period prior to participating if required.
- Evaluated as having a low likelihood of successful venipuncture by a certified phlebotomist.
Participate in this Research
Submitting this form will put you in contact with the main point of contact for this project. They will provide more information and determine if you meet all of the qualifications needed."*" indicates required fields
June 10, 2026
Education Complex and Gymnasium
12494 University Blvd
ED-0179
Orlando, FL 32816
Number of visits: 5
Adam Wells
Kinesiology