Aging and Chronic Knee Pain

Aging and Chronic Knee Pain

This research is being done in order to broaden our understanding of how pain mechanisms differ between older adults with chronic knee pain and pain-free older adults. Additionally, we hope to observe differences between how different muscles are activated during a knee extension in a group of older adults experiencing knee pain versus pain free (no knee pain) older adult group. We will compare these findings to a group of young adults to help determine the effect that aging has on both pain mechanisms as well as muscle activation.

We expect that you will be in this research study for approximately 1-2 weeks. You will be asked to come into the UCF CNS laboratory for 3 visits: one familiarization visit and two testing visits. Each visit will last at maximum 90 minutes. During the familiarization visit you will fill out some paperwork to learn about the upcoming protocols, conduct some baseline demographic measures, and then we will get you comfortable with the testing procedures. During one of the testing sessions, you will undergo a protocol for testing pain modulation. During the second testing session, you will be performing maximal voluntary contractions of the knee for muscle analysis.

Inclusion Qualifications:

  • Healthy adult between the ages of 18-25 years with no knee pain.
  • Healthy adult at least 50 years of age with no knee pain.
  • Healthy adult at least 50 years of age with knee pain.

Exclusion Qualifications:

You may not participate in this research opportunity if any of the following applies to you:
  • Current use of opioid medication
  • Chronic use of analgesic medication
  • Contraindication to the application of ice (uncontrolled hypertension defined as blood pressure > 140/90 mmHg, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise)
  • Any systemic medical conditions that impair sensation
  • Widespread pain condition, including fibromyalgia
  • History of orthopedic surgery or fracture within the previous 6 months
  • History of Total Knee Arthroplasty (TKA)
  • Premenopausal females
  • Ongoing participation in other interventions that may affect pain (e.g., physical therapy, acupuncture, chiropractic, etc.)
  • Body mass index > 35.0 kg/m2, but not less than 18.5 kg/m2
  • Major surgery or hospitalization within the previous 6 months
  • Heart attack within the previous 6 months
  • Self-reported fall within the previous 6 months
  • Treatment for cancer within the previous year
  • History of Stroke
  • Major neuromuscular and/or degenerative diseases (e.g., Myasthenia Gravis, Charcot-Marie-Tooth disease, Parkinson’s disease, ALS, Huntington’s disease, MS, etc.)
  • Uncontrolled hypertension or diabetes
  • Chronic kidney disease
  • Changes in medications or therapies that may alter hormone levels within the previous 6 months (e.g., testosterone replacement therapy)
  • Diagnosis of Alzheimer’s disease or severe cognitive impairment (≤9 on the mini–mental state examination)
  • Clotting disorders
  • Untreated deep vein thrombosis
  • Limb amputation

Participate in this Research

Submitting this form will put you in contact with the main point of contact for this project. They will provide more information and determine if you meet all of the qualifications needed.

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* Please note that completion of this form does not automatically enroll you or guarantee you a spot in this research opportunity. The information provided in this form will never be shared with 3rd parties. You can also unsubscribe from future notifications at any time.
UCF IRB#: STUDY00006772
PI: Matt S. Stock
IRB Expiration May 27, 2025
Recruitment End Date:
February 1, 2025
12494 University Blvd
Orlando, FL 32816
Time Commitment:
Number of visits: 3
Expected time per visit: 90 minutes
Type: T-shirt ($25 value)
Point of Contact:
Emily Parsowith
Faculty Advisors:
Matt Stock
Associated Units:
Physical Therapy
Exercise Physiology & Rehabilitation Science
Related Tags:
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