CHPS RESEARCH STUDIES

Brain-muscle communication after ACL injury

The general purpose of this study is to learn more about brain and muscle communication. We know that when you move, your brain and muscles communicate seamlessly. This helps you stay balanced and move smoothly. The study wants to look closely at how the brain controls the muscles. By understanding this better, we hope to help people who have been injured, like hurting their knees, by finding ways to improve their recovery.

Inclusion Qualifications:

Inclusion criteria – ACL group:

Age 18-35 years
History of primary unilateral ACL reconstruction (ACLR) within last 2 years
No history of any lower limb surgery besides the current ACLR
Medical clearance to initiate jogging

Inclusion criteria – Uninjured group:

Age 18-35 years
No history of lower extremity surgery
No history of lower extremity injury (defined as seeking medical attention) within last 2 years

Exclusion Qualifications:

You may not participate in this research opportunity if any of the following applies to you:

Exclusion criteria – All participants:

Current infection on lower limb
Known or diagnosed muscular abnormalities
History of endurance training (engaged in endurance training involving the lower limbs at least three times per week since at least 3 years)
History of cardiopulmonary disorder
History of diagnosed neurological disorder (e.g., stroke, epilepsy or seizure, neuropathy, migraine)
History of diagnosed psychiatric disorder (e.g., attention deficit hyperactivity disorder, depression, severe anxiety)
History of traumatic brain injury (e.g., diagnosed concussion)
Currently taking any medications which may influence objective clinical data (e.g., antispastics [muscle relaxers], anxiolytics [anxiety/depression], hypnotics [sleep], ant-epileptics [seizure])
Current low back pain that limits daily activities
Known pregnancy

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