Influence of Mirror Therapy on Corticospinal Responses in Amputees

Influence of Mirror Therapy on Corticospinal Responses in Amputees

The aim of this study is to investigate the effects of mirror therapy on corticospinal responses in unilateral transtibial amputees. Corticospinal excitability will be measured via transcranial magnetic stimulation, which is a non-invasive technique that measures brain function. Mirror therapy, in which a patient views their intact limb in a mirror giving the illusion that both limbs are intact, has previously been shown to be a useful tool for therapeutic use. The findings of this study have the potential to further evaluate mirror therapy as a treatment for pain relief and functional outcomes.

Inclusion Qualifications:

  • Healthy men and women between the ages of 18 and 65
  • Must have either 1) a unilateral below the knee transtibial amputation or 2) two intact limbs

Exclusion Qualifications:

You may not participate in this research opportunity if any of the following applies to you:
  • Neuromuscular disease (e.g. Parkinson’s, MS, ALS)
  • Metabolic disease (e.g. diabetes, thyroid disorder, metabolic syndrome)
  • Trouble using or controlling one’s muscles
  • Arthritis in the lower limbs (hips or knees)
  • History of cancer, stroke, or cardiovascular events
  • Physician mandated contraindication to exercise within the last six months
  • Epilepsy or history of convulsions or seizures
  • History of fainting or syncope
  • History of head trauma that was diagnosed as a concussion or associated with loss of consciousness
  • History of hearing problems or tinnitus
  • Cochlear implants
  • Implanted metal in the brain, skull, or elsewhere in the body
  • Implanted neurotransmitter
  • Cardiac pacemaker or intracardiac lines
  • Medication infusion device
  • Past problems with brain stimulation
  • Past problems of MRI
  • Use of muscle relaxants or benzodiazepines
  • Allergy to rubbing alcohol
  • Any other health related illnesses that would prohibit a participant from physical performance testing
  • History of knee injury
  • Lack of transportation to and from the laboratory

Participate in this Research

Submitting this form will put you in contact with the main point of contact for this project. They will provide more information and determine if you meet all of the qualifications needed.
    * Please note that completion of this form does not automatically enroll you or guarantee you a spot in this research opportunity. The information provided in this form will never be shared with 3rd parties. You can also unsubscribe from future notifications at any time.
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UCF IRB#: STUDY00001542
PI: Matt S. Stock, Ph.D.
IRB Expiration March 1, 2021
Recruitment End Date:
March 1, 2021
Partnership 1
12354 Research Parkway
Orlando, FL 32826
Time Commitment:
Number of visits: 1
Expected time per visit: 3 hours
Type: $20 Target Gift Card
Point of Contact:
Kylie Harmon
Faculty Advisors:
Matt Stock
Associated Units:
Physical Therapy
Exercise Physiology & Rehabilitation Science
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